Balybin E S, Vinnick L A
Medical Radiology Laboratory, Leprosy Research Institute, Russia.
Int J Lepr Other Mycobact Dis. 1994 Jun;62(2):225-8.
The contribution of some adaptation hormones to the process regulating production of autoantibodies to collagen (Abc) and elastin (Abe) was studied in leprosy (37 patients) and tuberculosis (31 patients). In both mycobacterioses the Abc and Abe titers were increased and inversely correlated with endogenous cortisol levels. In leprosy the antibody titers directly correlated with the triiodothyronine (T3) levels which were significantly higher than the values in healthy controls. A new approach to research for remedies and methods of preventing and curing autosensitization to connective tissue is suggested by combining medications according to individual endocrine and immune indices.
在麻风病患者（37例）和结核病患者（31例）中，研究了某些适应性激素对调节抗胶原蛋白自身抗体（Abc）和抗弹性蛋白自身抗体（Abe）产生过程的作用。在这两种分枝杆菌病中，Abc和Abe滴度均升高，且与内源性皮质醇水平呈负相关。在麻风病中，抗体滴度与三碘甲状腺原氨酸（T3）水平直接相关，而T3水平显著高于健康对照组的值。根据个体内分泌和免疫指标联合用药，为结缔组织自身致敏的防治药物及方法研究提供了一种新途径。
