Malone M, Harris A L, Luscombe D K
Albany College of Pharmacy, New York 12208.
J R Soc Med. 1994 Jul;87(7):386-9. doi: 10.1177/014107689408700705.
A general health status measure (the UK Sickness Impact Profile) was used to assess health-related quality of life in 212 cancer patients [143 women, mean (SD-standard deviation) age 55.3 (11.7) years] compared to 105 age-sex matched control subjects [71 women, mean (SD) age 54.7 (12.2) years]. The four main areas of impairment in the cancer patient group were work, recreation and pastimes, home management and sleep and rest. The majority of patients were unable to work or working shorter hours due to their disease. A diagnosis of cancer was likewise found to have a major impact on active leisure pursuits and led to reduced participation in social and community activities. Patients had particular problems in carrying out household chores and maintenance or repair work in the house. Many patients had difficulty sleeping at night and tended to sleep during the day or rest for much of the day. The majority of studies of quality of life in oncology patients concentrate upon alterations in symptoms, such measures would fail to detect impairment in the aspects described above. Greater attention should be directed towards addressing issues such as changes in employment status and the need for help in the home to improve the overall care of cancer patients.
采用一项综合健康状况测量工具(英国疾病影响量表)对212名癌症患者[143名女性,平均(标准差)年龄55.3(11.7)岁]的健康相关生活质量进行评估,并与105名年龄和性别匹配的对照对象[71名女性,平均(标准差)年龄54.7(12.2)岁]进行比较。癌症患者组受损的四个主要方面是工作、娱乐和消遣、家庭管理以及睡眠和休息。大多数患者因疾病无法工作或工作时间缩短。同样发现,癌症诊断对积极的休闲活动有重大影响,并导致参与社会和社区活动的机会减少。患者在做家务以及房屋维护或修理工作方面存在特别的问题。许多患者夜间睡眠困难,且往往白天睡觉或大部分时间都在休息。大多数关于肿瘤患者生活质量的研究都集中在症状的变化上,这类测量方法无法检测到上述方面的受损情况。应该更加关注解决诸如就业状况变化以及家庭帮助需求等问题,以改善癌症患者的整体护理。