Aghadiuno P U, Akang E E, Ladipo J K
Department of Pathology, University College Hospital, Ibadan, Nigeria.
J Natl Med Assoc. 1994 May;86(5):365-8.
This study reviews the clinicopathological features and survival of 18 Nigerian women with simultaneous bilateral breast cancer. Twelve (67%) of these patients had bilateral Burkitt's lymphoma of the breast. The average age of these patients was 22 years, and all of the women were pregnant or lactating at the time of initial clinical presentation. The remaining six patients (33%) had bilateral malignant epithelial neoplasms, with lobular carcinoma being present in four cases. The average age of patients with bilateral malignant epithelial tumors was 37 years. None of the 18 patients with simultaneous bilateral breast cancer survived for up to 2 years after diagnosis, indicating that bilateral synchronous breast cancer in Nigerian women is a rapidly progressive and aggressive disease.
本研究回顾了18例尼日利亚同时性双侧乳腺癌女性患者的临床病理特征及生存情况。其中12例(67%)患者为双侧乳腺伯基特淋巴瘤。这些患者的平均年龄为22岁,所有女性在初次临床表现时均处于妊娠或哺乳期。其余6例患者(33%)为双侧恶性上皮性肿瘤,其中4例为小叶癌。双侧恶性上皮性肿瘤患者的平均年龄为37岁。18例同时性双侧乳腺癌患者确诊后均未存活至2年,这表明尼日利亚女性的双侧同步性乳腺癌是一种快速进展且侵袭性强的疾病。