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[对结节病患者的皮质类固醇治疗]

[Corticosteroid treatment to patients with sarcoidosis].

作者信息

Nagai S, Izumi T

机构信息

Chest Disease Research Institute, Kyoto University.

出版信息

Nihon Rinsho. 1994 Jun;52(6):1633-42.

PMID:8046855
Abstract

Regarding the corticosteroid treatment to patients with sarcoidosis, two schools of thoughts can be recognized: the one in favor of early treatment in contrast to the one preferring late treatment. However, no final consensus has been obtained so far. We analysed ten years follow-up data of patients with sarcoidosis who were detected by health examination though they were asymptomatic. The results showed that the rate of improvement of chest abnormality was higher in the non-treated cases than in the treated ones. The possibility exists that this can be applied to the cases with symptoms at detection. In conclusion, from the present state of knowledge, the use of corticosteroids is justified only for symptomatic relief and control of disabling systemic involvement.

摘要

关于结节病患者的皮质类固醇治疗,存在两种观点:一种支持早期治疗,另一种则倾向于晚期治疗。然而,迄今为止尚未达成最终共识。我们分析了通过健康检查发现的无症状结节病患者的十年随访数据。结果显示,未治疗病例的胸部异常改善率高于治疗病例。这种情况有可能适用于在检查时出现症状的病例。总之,就目前的知识水平而言,使用皮质类固醇仅适用于缓解症状和控制导致残疾的全身受累情况。

相似文献

1
[Corticosteroid treatment to patients with sarcoidosis].[对结节病患者的皮质类固醇治疗]
Nihon Rinsho. 1994 Jun;52(6):1633-42.
2
[The effect of therapeutic intervention with corticosteroids on outcome and prognosis of sarcoidosis].[皮质类固醇治疗干预对结节病结局和预后的影响]
Zhonghua Jie He He Hu Xi Za Zhi. 2003 Jan;26(1):14-7.
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Corticosteroid therapy of intrathoracic sarcoidosis stages I and II--results of a controlled clinical trial.I期和II期胸内结节病的皮质类固醇治疗——一项对照临床试验的结果
Z Erkr Atmungsorgane. 1977 Jul;149(1):142-7.
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[Mediastinopulmonary sarcoidosis; the indications for corticosteroid therapy].[纵隔肺结节病;皮质类固醇治疗的指征]
Sem Hop. 1976 Nov 23;52(40):2263-8.
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[Interstitial nephropathies in sarcoidosis. Effect of corticosteroid therapy and long-term evolution. Retrospective study of 22 cases].[结节病中的间质性肾病。皮质类固醇治疗的效果及长期演变。对22例病例的回顾性研究]
Nephrologie. 1988;9(6):253-7.
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Aggressive therapy for neurosarcoidosis: long-term follow-up of 48 treated patients.神经结节病的积极治疗:48例接受治疗患者的长期随访
Arch Neurol. 2007 May;64(5):691-6. doi: 10.1001/archneur.64.5.691.
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[The treatment and prognosis of sarcoidosis. Apropos 53].[结节病的治疗与预后。关于53例]
An Med Interna. 2000 Oct;17(10):517-20.
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[Ocular sarcoidosis. Retrospective study of 18 cases].[眼部结节病。18例回顾性研究]
Arch Soc Esp Oftalmol. 2002 Jun;77(6):301-8.
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[Neurosarcoidosis of the central nervous system. Analysis of the long-term follow-up of 8 cases].[中枢神经系统结节病。8例长期随访分析]
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Prolonged use of methotrexate for sarcoidosis.甲氨蝶呤在结节病中的长期应用。
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引用本文的文献

1
Nonpulmonary manifestations of sarcoidosis.结节病的非肺部表现。
Curr Rheumatol Rep. 2002 Apr;4(2):170-8. doi: 10.1007/s11926-002-0013-1.