Nagai S, Izumi T
Chest Disease Research Institute, Kyoto University.
Nihon Rinsho. 1994 Jun;52(6):1633-42.
Regarding the corticosteroid treatment to patients with sarcoidosis, two schools of thoughts can be recognized: the one in favor of early treatment in contrast to the one preferring late treatment. However, no final consensus has been obtained so far. We analysed ten years follow-up data of patients with sarcoidosis who were detected by health examination though they were asymptomatic. The results showed that the rate of improvement of chest abnormality was higher in the non-treated cases than in the treated ones. The possibility exists that this can be applied to the cases with symptoms at detection. In conclusion, from the present state of knowledge, the use of corticosteroids is justified only for symptomatic relief and control of disabling systemic involvement.
关于结节病患者的皮质类固醇治疗,存在两种观点:一种支持早期治疗,另一种则倾向于晚期治疗。然而,迄今为止尚未达成最终共识。我们分析了通过健康检查发现的无症状结节病患者的十年随访数据。结果显示,未治疗病例的胸部异常改善率高于治疗病例。这种情况有可能适用于在检查时出现症状的病例。总之,就目前的知识水平而言,使用皮质类固醇仅适用于缓解症状和控制导致残疾的全身受累情况。