Kogure M
Department of Ophthalmology, Tokyo Women's Medical College.
Nihon Rinsho. 1994 Jun;52(6):1654-8.
Corticosteroid are the main treatment in both systemic and ocular sarcoidosis. Most cases of ocular sarcoidosis, such as iridocyclitis, retinal periphlebitis, optic disc inflammation, vitritis and snowballs can be managed with topical or subconjunctival injections of corticosteroids. However, only rarely cases are systemic steroids indicated. High doses of systemic steroids are effective in unusual manifestations of retinal vein occlusions, retinal and optic disc neovascularization and vitreous hemorrhage. Systemic corticosteroids starting with moderately high doses (40-60 mg/day) with slow tapering according to the clinical response is necessary. Photocoagulation has not been widely used in the treatment of neovascularization, secondary to sarcoidosis.
皮质类固醇是系统性和眼部结节病的主要治疗方法。大多数眼部结节病病例,如虹膜睫状体炎、视网膜静脉周围炎、视盘炎、玻璃体炎和雪球样病变,可通过局部或结膜下注射皮质类固醇进行治疗。然而,仅在极少数情况下才需要使用全身性类固醇。高剂量全身性类固醇对视网膜静脉阻塞、视网膜和视盘新生血管形成以及玻璃体积血的罕见表现有效。开始使用中等高剂量(40 - 60毫克/天)的全身性皮质类固醇并根据临床反应缓慢减量是必要的。光凝术在结节病继发的新生血管形成治疗中尚未得到广泛应用。