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[甲状腺毒性甲状腺肿患者外周血淋巴细胞氧化还原酶活性的细胞化学定义]

[Cytochemical definition of oxidation-reduction enzyme activity peripheral blood lymphocytes in patients with thyrotoxic goiter].

作者信息

Podilćhak M D, Makar D A, Terletska L M

出版信息

Klin Khir (1962). 1993(12):44-6.

PMID:8046872
Abstract

In patients with thyrotoxic goiter (TTG), a significant decrease in the activity of alpha-glycerophosphate-dehydrogenase and adenosinetriphosphatase of the peripheric blood lymphocytes was revealed. The lowest indices were noted in patients with a severe form of TTG, who underwent strumectomy. After conservative and operative treatment of TTG, a tendency for normalization of the enzyme activity was observed. Study of changes in the activity of the oxidation-reduction lymphocytic enzymes in dynamics permits to assess the severity of the course of TTG and to control and predict the effectiveness of treatment as well.

摘要

在甲状腺毒性甲状腺肿(TTG)患者中,发现外周血淋巴细胞的α-甘油磷酸脱氢酶和三磷酸腺苷酶活性显著降低。在接受甲状腺切除术的重度TTG患者中观察到最低指标。对TTG进行保守和手术治疗后,观察到酶活性有正常化的趋势。动态研究氧化还原淋巴细胞酶活性的变化有助于评估TTG病程的严重程度,并控制和预测治疗效果。

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