Griffith P, James B, Cropp A
Critical Care/Heart, Lung and Blood Nursing Service, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, MD.
Nurs Res. 1994 Jul-Aug;43(4):203-6.
The purpose of this study was to determine the safety and efficacy of 2% nitroglycerin ointment to facilitate venous cannulation. In a double-blind experimental design, 80 adult subjects were randomly assigned to receive a 2% nitroglycerin ointment or a placebo ointment prior to cannulation. Variables measured before and after ointment application included heart rate, electrocardiogram, vein size, and presence of headache. No statistically significant differences were found in vein size or adverse effects following nitroglycerin ointment application.
本研究的目的是确定2%硝酸甘油软膏促进静脉插管的安全性和有效性。在一项双盲实验设计中，80名成年受试者在插管前被随机分配接受2%硝酸甘油软膏或安慰剂软膏。在涂抹软膏前后测量的变量包括心率、心电图、静脉大小和是否出现头痛。应用硝酸甘油软膏后，静脉大小或不良反应方面未发现统计学上的显著差异。
