Corsi-Cabrera M, Ponce-De-Leon M, Juarez J, Ramos J
Departamento de Psicofisiología, Facultad de Psicología, Universidad Nacional Autónoma de México, México D.F.
Physiol Behav. 1994 Jun;55(6):1021-7. doi: 10.1016/0031-9384(94)90383-2.
Effects of 72 h of paradoxical sleep deprivation (PSD) and stress on the waking EEG of rats were studied using the water tank technique. EEG was recorded at left and right parietal cortex and the spectrum was analyzed before PSD, after 24, 48, and 72 h of PSD, and 24 h after recovery. Absolute and relative power and interparietal correlation were obtained. The same analyses were performed on a larger platform group and on a cold water-stressed group. The following significant changes were observed on the waking EEG: PSD produced a decrease in interparietal correlation, an increase in absolute and relative power between 7.3 and 9.3 Hz, and a decrease in the delta band relative power. The PSD effect on relative power was less specific on absolute power; relative power between 7.3 and 9.3 Hz was also increased in the large platform control group. Interparietal correlation was also decreased in both control groups but in the water-stressed animals it followed a different time course. The present findings suggest that PSD may affect brain function by increasing the level of hippocampal arousal, whereas the combination of stress and PSD affects interhemispheric coupling.
采用水槽技术研究了72小时异相睡眠剥夺（PSD）和应激对大鼠清醒脑电图的影响。在PSD前、PSD 24、48和72小时后以及恢复24小时后，记录左右顶叶皮质的脑电图并分析其频谱。获得绝对功率、相对功率和顶叶间相关性。对较大平台组和冷水应激组进行相同的分析。在清醒脑电图上观察到以下显著变化：PSD导致顶叶间相关性降低，7.3至9.3 Hz之间的绝对功率和相对功率增加，以及δ频段相对功率降低。PSD对相对功率的影响比对绝对功率的影响特异性小；在大平台对照组中，7.3至9.3 Hz之间的相对功率也增加。两个对照组的顶叶间相关性也降低，但在应激动物中，其变化时间过程不同。目前的研究结果表明，PSD可能通过提高海马觉醒水平来影响脑功能，而应激和PSD的联合作用则影响半球间耦合。
