Palva H L, Koivisto O, Palva I P
Acta Haematol. 1975;53(2):105-8. doi: 10.1159/000208163.
A 64-year-old farmer developed aplastic anaemia after exposure to 2-methyl-4-chlorphenoxyactic acid while spraying weed killer. Muscular weakness, haemorrhagic gastritis and slight signs of liver damage occurred at the same time. All these symptoms, including blood dyscrasia , are consistent with those described as toxic effects of chlorphenoxyacetic acids in animal experiments. A causal relationship between aplastic anaemia and the 2-methyl-4-chlorphenoxyacetic acid thus seems probable. The anaemia was reversible, but the case serves as a warning that careful safety measures are required during the use of chlorphenoxyacetic acids and related compounds.
一名64岁的农民在喷洒除草剂时接触了2-甲基-4-氯苯氧基乙酸后患上再生障碍性贫血。同时出现了肌肉无力、出血性胃炎和轻微的肝损伤迹象。所有这些症状，包括血液恶病质，都与动物实验中描述的氯苯氧基乙酸的毒性作用一致。因此，再生障碍性贫血与2-甲基-4-氯苯氧基乙酸之间似乎存在因果关系。贫血是可逆的，但该病例警示人们，在使用氯苯氧基乙酸及其相关化合物时需要采取谨慎的安全措施。
