Shilova S V, Solov'ev V N
Antibiotiki. 1975 Jan;20(1):48-53.
Resistance parameters of 17 clinical strains of Staph, aureus to oxacillin were studied with the methods of agar diffusion and serial dilutions in liquid and solid media. Statistically reliable correlation between the parameter values of resistance and growth inhibition zone diameters on diffusion into agar of 100 gamma of oxacillin was found. The latter method provided classification of the strains into groups with high, intermediate and low resistance levels. However, calculation of the resistance parameters according to the corresponding correlation equation was not enough correct for providing distinction in the resistance levels within the groups.
采用琼脂扩散法以及在液体和固体培养基中连续稀释的方法,研究了17株金黄色葡萄球菌临床菌株对苯唑西林的耐药参数。发现耐药参数值与100微克苯唑西林扩散到琼脂中的抑菌圈直径之间存在统计学上可靠的相关性。后一种方法可将菌株分为高、中、低耐药水平组。然而,根据相应的相关方程计算耐药参数,对于区分组内耐药水平并不足够准确。