• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

免疫缺陷与婴幼儿骨和关节感染。

Immunodeficiency and infantile bone and joint infection.

作者信息

Kuo K N, Lloyd-Roberts G C, Orme I M, Soothill J F

出版信息

Arch Dis Child. 1975 Jan;50(1):51-6. doi: 10.1136/adc.50.1.51.

DOI:10.1136/adc.50.1.51
PMID:804866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1544479/
Abstract

Fifteen patients with infantile bone and joint infections were studied immunologically and clinically, 3 at the time of illness and 12 later. Abnormality of immunoglobulins, or complement, or phagocytes was found in 9 patients; 6 were within normal limits for the tests undertaken. Immunodeficiency is probably responsible for the subdued clinical signs of infection and for delayed diagnosis in some patients. It was also related to the extent of femoral head damage in infective arthritis of the hip and to the incidence of wound infection in late elective surgery.

摘要

对15例婴儿骨与关节感染患者进行了免疫学和临床研究,其中3例在患病时进行研究,12例在之后进行研究。9例患者发现免疫球蛋白、补体或吞噬细胞异常;6例在进行的检测中处于正常范围。免疫缺陷可能是导致感染临床症状不明显以及部分患者诊断延迟的原因。它还与髋关节感染性关节炎中股骨头损伤的程度以及择期手术后期伤口感染的发生率有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b52a/1544479/6b621a962b4b/archdisch00845-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b52a/1544479/94424935a99a/archdisch00845-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b52a/1544479/fa7f94d359cd/archdisch00845-0060-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b52a/1544479/6b621a962b4b/archdisch00845-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b52a/1544479/94424935a99a/archdisch00845-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b52a/1544479/fa7f94d359cd/archdisch00845-0060-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b52a/1544479/6b621a962b4b/archdisch00845-0061-a.jpg

相似文献

1
Immunodeficiency and infantile bone and joint infection.免疫缺陷与婴幼儿骨和关节感染。
Arch Dis Child. 1975 Jan;50(1):51-6. doi: 10.1136/adc.50.1.51.
2
Pediatric orthopedic infections: missed diagnoses.小儿骨科感染:漏诊
Pediatr Ann. 1999 Dec;28(12):718-20. doi: 10.3928/0090-4481-19991201-03.
3
Myasthenia gravis: the role of immunological deficiency.重症肌无力:免疫缺陷的作用。
Ann N Y Acad Sci. 1976;274:461-7. doi: 10.1111/j.1749-6632.1976.tb47707.x.
4
[Clinical and practical significance of alpha-antistaphylolysin (ASTA) determination in orthopedic diseases].[α-抗葡萄球菌溶血素(ASTA)测定在骨科疾病中的临床及实际意义]
Z Orthop Ihre Grenzgeb. 1969 Nov;107(1):144-51.
5
Clinical and molecular aspects of the pathogenesis of Staphylococcus aureus bone and joint infections.金黄色葡萄球菌骨与关节感染发病机制的临床及分子学方面
J Med Microbiol. 1996 Mar;44(3):157-64. doi: 10.1099/00222615-44-3-157.
6
Evaluation of the child with immunodeficiency disorder.免疫缺陷疾病患儿的评估。
Pediatr Ann. 2011 Apr;40(4):205-11. doi: 10.3928/00904481-20110316-08.
7
Staphylococcus aureus bone and joint infection.金黄色葡萄球菌骨与关节感染
J Infect. 2002 Apr;44(3):143-51. doi: 10.1053/jinf.2001.0952.
8
Sub-units of the first complement component in immunologic deficiency syndromes: independence of Cls and Clq.免疫缺陷综合征中第一补体成分的亚单位:C1s与C1q的独立性
Clin Exp Immunol. 1970 Aug;7(2):133-7.
9
[X-ray diagnosis of inflammatory bone- and joint diseases].
Chirurg. 1970 May;41(5):198-203.
10
Familial opsonization defect associated with fatal infantile dermatitis, infections, and histiocytosis.与致命性婴儿皮炎、感染及组织细胞增多症相关的家族性调理素缺陷。
Arch Dis Child. 1975 Apr;50(4):311-7. doi: 10.1136/adc.50.4.311.

引用本文的文献

1
Osteomyelitis. Common causes and treatment recommendations.骨髓炎。常见病因及治疗建议。
Drugs. 1993 Jan;45(1):29-43. doi: 10.2165/00003495-199345010-00004.
2
Immune deficiency, thrombocytopenia and osteomyelitis in pediatric patients.儿科患者的免疫缺陷、血小板减少症和骨髓炎
Yale J Biol Med. 1978 Jul-Aug;51(4):435-40.
3
Pediatric osteomyelitis and septic arthritis: the pathology of neonatal disease.小儿骨髓炎和化脓性关节炎:新生儿疾病的病理学

本文引用的文献

1
Septic arthritis of the hip and osteomyelitis of the upper end of the femur in infants.婴儿髋关节化脓性关节炎及股骨上端骨髓炎
J Bone Joint Surg Br. 1960 Feb;42-B:11-20. doi: 10.1302/0301-620X.42B1.11.
2
Idiopathic hyperglycinemia and hyperglycinuria: a new disorder of amino acid metabolism. I.特发性高甘氨酸血症和高甘氨酸尿症:一种新的氨基酸代谢紊乱。I.
Pediatrics. 1961 Apr;27:522-38.
3
In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood.人多形核白细胞的体外杀菌能力:儿童慢性肉芽肿病中活性降低。
Yale J Biol Med. 1979 Sep-Oct;52(5):423-48.
J Clin Invest. 1967 Apr;46(4):668-79. doi: 10.1172/JCI105568.
4
Phagocytosis in the newborn infant: humoral and cellular factors.新生儿的吞噬作用:体液和细胞因子
J Pediatr. 1969 Feb;74(2):255-9. doi: 10.1016/s0022-3476(69)80073-9.
5
Disturbed epiphysial growth at the knee after osteomyelitis in infancy.婴儿期骨髓炎后膝关节骨骺生长紊乱。
J Bone Joint Surg Br. 1970 Nov;52(4):692-703.
6
A familial deficiency of the phagocytosis-enhancing activity of serum related to a dysfunction of the fifth component of complement (C5).一种与补体第五成分(C5)功能障碍相关的血清吞噬作用增强活性的家族性缺陷。
N Engl J Med. 1970 Feb 12;282(7):354-8. doi: 10.1056/NEJM197002122820702.
7
Immunological studies in children undergoing tonsillectomy.接受扁桃体切除术儿童的免疫学研究。
Clin Exp Immunol. 1973 Jul;14(3):347-57.
8
Chronic granulomatous disease: quantitative clinicopathological relationships.慢性肉芽肿病:定量临床病理关系
Arch Dis Child. 1970 Feb;45(239):24-32. doi: 10.1136/adc.45.239.24.
9
Immunoconglutinin and complement changes in children with acute nephritis.急性肾炎患儿免疫粘连素及补体的变化
Clin Exp Immunol. 1969 Dec;5(6):557-66.
10
Gamma-M deficiency predisposing to meningococcal septicaemia.γ-M缺乏易引发脑膜炎球菌败血症。
Br Med J. 1967 Dec 9;4(5579):583-6. doi: 10.1136/bmj.4.5579.583.