Hosoya H, Komatsu S, Shimizu T, Inagaki M, Ikegami M, Yazaki K
Department of Biological Science, Faculty of Science, Hiroshima University, Japan.
Biochem Biophys Res Commun. 1994 Jul 29;202(2):1127-33. doi: 10.1006/bbrc.1994.2045.
A 100kD microtubule-bundling protein dynamin was phosphorylated in vitro by cdc2 kinase to approximately 1 mol of phosphate/mol of dynamin at a serine residue. These phosphorylations of dynamin greatly reduced its binding ability to microtubules.
一种100kD的微管成束蛋白发动蛋白在体外被细胞分裂周期蛋白2激酶磷酸化，在一个丝氨酸残基上，磷酸化程度约为每摩尔发动蛋白1摩尔磷酸。发动蛋白的这些磷酸化大大降低了其与微管的结合能力。
