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主动脉冠状动脉搭桥手术后无症状性缺血的血管造影结果。

Angiographic findings of silent ischaemia following aortocoronary bypass surgery.

作者信息

Lundbom J, Myhre H O, Ystgaard B, Tromsdal A, Aakhus S, Bjørnstad K, Bolz K D, Levang O W

机构信息

Department of Surgery, Regional Hospital, Trondheim, Norway.

出版信息

Cardiovasc Surg. 1994 Jun;2(3):398-402.

PMID:8049984
Abstract

Silent ischaemia, defined as ST-depression > or = 1 mm without chest pain, was found on exercise testing in 22 (10.7%) of 206 patients who underwent aortocoronary bypass surgery in the period from March 1983 to November 1985. Exercise testing was performed 4.9 (range 3.6-6.7) years after operation on an electrically braked bicycle. Sixteen of the 22 patients were free from chest pain, while the remaining six had slight to moderate angina pectoris on exercise. Coronary angiography was performed in 21 patients with silent ischaemia; one of the 22 patients died before this investigation. Some 13 patients had one or more occluded grafts, one a new stenosis in a native vessel and five incomplete myocardial revascularization. For the remaining two patients, no aetiology for the ischaemia was found, and revascularization appeared to be complete. Before surgery, 13 patients had three-vessel disease, six two-vessel disease and three one-vessel disease. At follow-up, two patients had three-vessel disease, ten two-vessel disease and seven one-vessel disease. The value of identifying patients with silent ischaemia after aortocoronary bypass surgery with regard to life expectancy and quality is controversial. Subsets of patients, namely, those with main-stem stenosis and three-vessel disease, may benefit from secondary operation. Identification of these patients may therefore be of clinical importance.

摘要

无症状性缺血定义为无胸痛情况下ST段压低≥1毫米,在1983年3月至1985年11月期间接受主动脉冠状动脉搭桥手术的206例患者中,有22例(10.7%)在运动试验中被发现。运动试验在术后4.9年(范围3.6 - 6.7年)通过电动刹车自行车进行。22例患者中有16例无胸痛,其余6例在运动时有轻度至中度心绞痛。对21例无症状性缺血患者进行了冠状动脉造影;22例患者中有1例在此次检查前死亡。约13例患者有一个或多个移植血管闭塞,1例为自身血管出现新的狭窄,5例心肌血运重建不完全。其余2例患者未发现缺血病因,且血运重建似乎是完全的。手术前,13例患者为三支血管病变,6例为两支血管病变,3例为单支血管病变。随访时,2例患者为三支血管病变,10例为两支血管病变,7例为单支血管病变。关于主动脉冠状动脉搭桥手术后识别无症状性缺血患者对预期寿命和生活质量的价值存在争议。部分患者亚组,即主干狭窄和三支血管病变患者,可能从二次手术中获益。因此识别这些患者可能具有临床重要性。

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