Yong W H, Mattia A R, Ferraro M J
Clinical Microbiology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
J Clin Microbiol. 1994 May;32(5):1360-1. doi: 10.1128/jcm.32.5.1360-1361.1994.
The fecal lactoferrin assay was more sensitive (75%) than methylene blue microscopy (40%) for the detection of leukocytes in Clostridium difficile toxin-positive fecal samples. Although limited sensitivity and specificity precludes its use as a laboratory screening test, it may be a more useful initial test in an algorithm for clinically suspected C. difficile-associated disease.
在艰难梭菌毒素阳性粪便样本中检测白细胞时,粪便乳铁蛋白检测比亚甲蓝显微镜检查更敏感(分别为75%和40%)。尽管其敏感性和特异性有限,无法用作实验室筛查试验,但在临床疑似艰难梭菌相关疾病的检测流程中,它可能是更有用的初始检测方法。