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粪便乳铁蛋白乳胶凝集试验与亚甲蓝显微镜检查在艰难梭菌相关性疾病中检测粪便白细胞的比较

Comparison of fecal lactoferrin latex agglutination assay and methylene blue microscopy for detection of fecal leukocytes in Clostridium difficile-associated disease.

作者信息

Yong W H, Mattia A R, Ferraro M J

机构信息

Clinical Microbiology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114.

出版信息

J Clin Microbiol. 1994 May;32(5):1360-1. doi: 10.1128/jcm.32.5.1360-1361.1994.

DOI:10.1128/jcm.32.5.1360-1361.1994
PMID:8051268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC263702/
Abstract

The fecal lactoferrin assay was more sensitive (75%) than methylene blue microscopy (40%) for the detection of leukocytes in Clostridium difficile toxin-positive fecal samples. Although limited sensitivity and specificity precludes its use as a laboratory screening test, it may be a more useful initial test in an algorithm for clinically suspected C. difficile-associated disease.

摘要

在艰难梭菌毒素阳性粪便样本中检测白细胞时,粪便乳铁蛋白检测比亚甲蓝显微镜检查更敏感(分别为75%和40%)。尽管其敏感性和特异性有限,无法用作实验室筛查试验,但在临床疑似艰难梭菌相关疾病的检测流程中,它可能是更有用的初始检测方法。

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Comparison of fecal lactoferrin latex agglutination assay and methylene blue microscopy for detection of fecal leukocytes in Clostridium difficile-associated disease.粪便乳铁蛋白乳胶凝集试验与亚甲蓝显微镜检查在艰难梭菌相关性疾病中检测粪便白细胞的比较
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本文引用的文献

1
Diagnosis and treatment of Clostridium difficile colitis.艰难梭菌结肠炎的诊断与治疗
JAMA. 1993 Jan 6;269(1):71-5.
2
Clostridium difficile: clinical disease and diagnosis.艰难梭菌:临床疾病与诊断
Clin Microbiol Rev. 1993 Jul;6(3):251-65. doi: 10.1128/CMR.6.3.251.
3
Comparison of four methods in the diagnosis of Clostridium difficile disease.四种方法在艰难梭菌病诊断中的比较。
Eur J Clin Microbiol Infect Dis. 1993 Nov;12(11):882-6. doi: 10.1007/BF02000416.
4
Measurement of fecal lactoferrin as a marker of fecal leukocytes.测量粪便乳铁蛋白作为粪便白细胞的标志物。
J Clin Microbiol. 1992 May;30(5):1238-42. doi: 10.1128/jcm.30.5.1238-1242.1992.
5
Antibiotic-associated diarrhea.抗生素相关性腹泻
Clin Infect Dis. 1992 Oct;15(4):573-81. doi: 10.1093/clind/15.4.573.