Bhopal R S, Phillimore P, Moffatt S, Foy C
Department of Epidemiology and Public Health, Medical School, School of Health Care Sciences, Newcastle.
J Epidemiol Community Health. 1994 Jun;48(3):237-47. doi: 10.1136/jech.48.3.237.
To determine whether there was excess ill health in people living near a coking works, and if so whether it was related to exposure to coking works' emissions.
Populations varying in proximity to the coking works were compared with control populations. Health data were correlated with available environmental data.
Analysis of routinely collected mortality, cancer registration, and birth statistics; community survey using self completed postal questionnaires; retrospective analysis of general practice (GP) records; tests of respiratory function; and analysis of available environmental data.
Study and control populations were comparable in terms of response rates, gender, and most socioeconomic indicators. For adults, age standardised mortality and cancer rates of the population closest to the coking works were comparable with those for the district as a whole. Gender ratios, birthweight, and stillbirth rates were comparable in the study and control populations. For several indicators of respiratory health including cough, sinus trouble, glue ear, and wheeze (but not for asthma and chronic bronchitis) there was a gradient of self reported ill health, with the highest prevalence in areas closest to the works. For example, sinus trouble was reported by 20% of adults and 13% of children in the area closest to the works compared with 13% and 6% respectively in the control area. GP consultations for respiratory disorders increased when pollution (measured by SO2 levels) was high: annual consultation rates per 1000 varied from 752 in the top group of daily pollution levels to 424 in the bottom group. Analysis of locally collected smoke and SO2 data indicated that SO2 concentrations were highest closest to the works and, after closure of the coking works, the number of days on which SO2 and smoke levels exceeded 100 micrograms/m3 and 90 micrograms/m3, respectively, fell steeply.
Routinely available indicators failed to provide convincing evidence that the coking works had harmed health. Self report and GP consultations indicated that respiratory ill health in the people living close to the works was worse than expected. Some of the excess probably resulted from exposure to coking works emissions. The health effects of relatively low level but intermittently high air pollution from a point source may be subtle, contributing to respiratory morbidity, but not apparent in analysis of routine health indicators.
确定居住在炼焦厂附近的人群是否存在更多健康问题,若存在,是否与接触炼焦厂排放物有关。
将不同距离炼焦厂的人群与对照人群进行比较。健康数据与可用的环境数据相关联。
分析常规收集的死亡率、癌症登记和出生统计数据;使用自行填写的邮政问卷进行社区调查;对全科医生(GP)记录进行回顾性分析;呼吸功能测试;以及对可用环境数据进行分析。
研究人群和对照人群在回复率、性别和大多数社会经济指标方面具有可比性。对于成年人,最靠近炼焦厂的人群的年龄标准化死亡率和癌症发病率与整个地区的相当。研究人群和对照人群的性别比、出生体重和死产率相当。对于包括咳嗽、鼻窦问题、胶耳和喘息(但不包括哮喘和慢性支气管炎)在内的几个呼吸健康指标,自我报告的健康问题存在梯度差异,在最靠近工厂的地区患病率最高。例如,在最靠近工厂的地区,20%的成年人和13%的儿童报告有鼻窦问题,而对照地区分别为13%和6%。当污染(以二氧化硫水平衡量)较高时,因呼吸系统疾病进行的全科医生诊疗增加:每1000人的年度诊疗率从每日污染水平最高组的752人次到最低组的424人次不等。对当地收集的烟尘和二氧化硫数据的分析表明,最靠近工厂的地方二氧化硫浓度最高,炼焦厂关闭后,二氧化硫和烟尘水平分别超过100微克/立方米和90微克/立方米的天数急剧下降。
常规可用指标未能提供令人信服的数据表明炼焦厂损害了健康。自我报告和全科医生诊疗表明,居住在工厂附近的人群的呼吸健康问题比预期的更严重。部分额外的健康问题可能是由于接触炼焦厂排放物所致。来自点源的相对低水平但间歇性高浓度空气污染对健康的影响可能很细微,会导致呼吸系统发病,但在常规健康指标分析中并不明显。