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兔半月板同种异体移植辐照:术后六个月力学性能研究

Irradiated meniscal allotransplants of rabbits: study of the mechanical properties at six months postoperation.

作者信息

Yahia L, Zukor D

机构信息

Biomechanics-Biomaterials Group, Biomedical Engineering Institute, Ecole Polytechnique, Montréal, Québec, Canada.

出版信息

Acta Orthop Belg. 1994;60(2):210-5.

PMID:8053322
Abstract

In this study, the long-term effects of gamma irradiation were investigated on the indentation properties of rabbits' meniscal allotransplants. Three groups, i.e. fresh, frozen and frozen irradiated allotransplants, were studied at 6 months postoperatively. Contralateral menisci served as controls in each group. Treatment effects were assessed using three mechanical parameters, i.e. compliance to long-term creep (J(R)), compliance to rapid load (Jmu) and viscoelastic characteristic time (tau i). Comparison of the three groups showed that compliance to long-term creep of the frozen irradiated menisci was significantly reduced. This suggests that at 6 months postoperatively, the frozen irradiated allotransplants were less viscous compared to fresh or frozen transplants.

摘要

在本研究中,研究了γ射线辐照对兔半月板同种异体移植体压痕特性的长期影响。术后6个月对三组进行了研究,即新鲜、冷冻和冷冻辐照同种异体移植体。每组均以对侧半月板作为对照。使用三个力学参数评估治疗效果,即长期蠕变柔量(J(R))、快速加载柔量(Jmu)和粘弹性特征时间(tau i)。三组比较表明,冷冻辐照半月板的长期蠕变柔量显著降低。这表明,术后6个月时,冷冻辐照同种异体移植体与新鲜或冷冻移植体相比粘性较小。

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