Shih C C
Med Phys. 1975 Jan-Feb;2(1):9-13. doi: 10.1118/1.594157.
We propose the use of high energy electrons in a strong local magnetic field as the ionizing beam in radiation therapy. A high kinetic energy insures that the electrons will penetrate to deep-seated tumor masses. A high magnetic field of several tesla in the region encompassing the tumor will confine the high energy electrons to the tumor volume before the scattering of the beam becomes excessive, thus producing an enhanced electron "Bragg peak" and highly localized strong radiation dose. The conclusions are based on a detailed Monte Carlo model which includes Landau straggling, multiple scattering, and the space dependence of the magnetic field.
我们提议在放射治疗中使用处于强局部磁场中的高能电子作为电离束。高动能确保电子能够穿透到深部肿瘤团块。在包含肿瘤的区域施加几特斯拉的强磁场,将使高能电子在束流散射变得过大之前被限制在肿瘤体积内,从而产生增强的电子“布拉格峰”和高度局部化的强辐射剂量。这些结论基于一个详细的蒙特卡罗模型,该模型包括朗道散射、多次散射以及磁场的空间依赖性。