Dynarowicz I, Paprocki M
Department of Pharmacology, Faculty of Veterinary Medicine, University of Agriculture and Technology, Olsztyn, Poland.
Arch Vet Pol. 1993;33(1-2):39-45.
Activities of catechol-O-methyltransferase (COMT), total monoamine oxidase (MAO) and both types of MAO-A and MAO-B activities were examined in uterine artery on the 0-2nd, 13-14th and 16-18th days of the oestrous cycle in pigs. It was shown that activity of COMT was the lowest on the 0-2nd day, while on the 16-18th day of the oestrous cycle it increased by 52.4% (p < 0.05). Total activity of MAO was the highest at periovulatory phase, whereas on days 13-14 and 16-18 of oestrous cycle is was lower by 83.5% (p < 0.01) and 58.1% (p < 0.01) compared with its activity at periovulatory phase, and was higher on day 16-18 by 153.3% (p < 0.01) in relation to the luteal phase (13-14th day). MAO-A activity was 31.3% (p < 0.01) and MAO-B 62.5% (p < 0.05) of the total activity of MAO. Their activities were also highest at periovulatory phase, then decreased by 86.8-87.4% (p < 0.01) on 13-14th day and by 54.8-57.5% (p < 0.01) or 16-18th day of oestrous cycle. Activities of MAO-A and MAO-B were higher by 223.0-258.2% (p < 0.01) on 16-18th day in relation to the luteal phase (13-14th day). On that base we suppose that variations of COMT and MAO activities can significantly change the catecholamines content in the blood vessels of reproductive organs of pigs.
在母猪发情周期的第0 - 2天、第13 - 14天和第16 - 18天，检测了子宫动脉中儿茶酚 - O - 甲基转移酶（COMT）、总单胺氧化酶（MAO）以及MAO - A和MAO - B两种类型的活性。结果表明，COMT活性在第0 - 2天最低，而在发情周期的第16 - 18天增加了52.4%（p < 0.05）。MAO的总活性在排卵前期最高，而在发情周期的第13 - 14天和第16 - 18天，与排卵前期相比分别降低了83.5%（p < 0.01）和58.1%（p < 0.01），与黄体期（第13 - 14天）相比，在第16 - 18天升高了153.3%（p < 0.01）。MAO - A活性占MAO总活性的31.3%（p < 0.01），MAO - B占62.5%（p < 0.05）。它们的活性在排卵前期也最高，然后在发情周期的第13 - 14天降低了86.8 - 87.4%（p < 0.01），在第16 - 18天降低了54.8 - 57.5%（p < 0.01）。与黄体期（第13 - 14天）相比，MAO - A和MAO - B的活性在第16 - 18天升高了223.0 - 258.2%（p < 0.01）。基于此，我们推测COMT和MAO活性的变化可能会显著改变母猪生殖器官血管中的儿茶酚胺含量。
