蝶窦腺样囊性癌一例新病例的细胞遗传学发现
Cytogenetic findings in a new case of adenoid cystic carcinoma arising in sphenoidal sinus.
作者信息
López-Ginés C, Cerdá-Nicolás M, Llombart-Bosch A
机构信息
Department of Pathology, University of Valencia, Spain.
出版信息
Cancer Genet Cytogenet. 1994 Jul 15;75(2):150-2. doi: 10.1016/0165-4608(94)90169-4.
We studied a case of adenoid cystic carcinoma. Cytogenetic analysis was performed on short-term culture, and the karyotype revealed only an abnormal cell line with the following changes: partial trisomy 5q, 6q deletion, monosomy of chromosome 9,der(10)t(10;15), a possible ring chromosome 22, and loss of the Y chromosome. The implication of chromosomes 6 and 9 is considered in relation to the karyotypic evolution of this type of tumor.
我们研究了一例腺样囊性癌。对短期培养物进行了细胞遗传学分析，核型显示仅存在一条异常细胞系，有以下变化：5q部分三体、6q缺失、9号染色体单体、der(10)t(10;15)、一条可能的22号环状染色体以及Y染色体缺失。结合此类肿瘤的核型演变对6号和9号染色体的意义进行了探讨。
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