患有胸腺淋巴萎缩的蛋白质 - 热量营养不良儿童的致命感染。
Fatal infections in protein-calorie malnourished children with thymolymphatic atrophy.
作者信息
Purtilo D T, Connor D H
出版信息
Arch Dis Child. 1975 Feb;50(2):149-52. doi: 10.1136/adc.50.2.149.
Abstract
The clinicopathological features of 25 children who died with protein-calorie malnutrition were studied. All but four subjects were found at necropsy to have nutritional thymectomy and all but 3 died of infectious diseases. The infectious agents were chiefly intracellular micro-organisms including miliary tuberculosis, Herpes simplex, varicella, measles, Pneumocystis carinii, and Plasmodium falciparum. Staphylococcal infections, salmonellosis, shigellosis, strongyloidiasis, and hookworm were other significant infectious agents. Nutritionally acquired defective immunity, especially cell-mediated immunity, probably permitted these infectious agents to multiply and to disseminate widely.
摘要
对25例死于蛋白质 - 热量营养不良的儿童的临床病理特征进行了研究。尸检发现，除4例受试者外，其余均有营养性胸腺萎缩，除3例之外，其余均死于传染病。感染因子主要是细胞内微生物，包括粟粒性结核、单纯疱疹、水痘、麻疹、卡氏肺孢子虫和恶性疟原虫。葡萄球菌感染、沙门氏菌病、志贺氏菌病、粪类圆线虫病和钩虫病是其他重要的感染因子。营养性获得性免疫缺陷，尤其是细胞介导免疫，可能使这些感染因子得以繁殖并广泛传播。
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Fatal infections in protein-calorie malnourished children with thymolymphatic atrophy.患有胸腺淋巴萎缩的蛋白质 - 热量营养不良儿童的致命感染。
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本文引用的文献
1
Use of Body Measurements in the School Health Program.学校健康计划中身体测量的应用。
Am J Public Health Nations Health. 1946 Dec;36(12):1365-86.
2
Decreased brain weight in malnutrition and its implications.营养不良时脑重量减轻及其影响
East Afr Med J. 1965 Nov;42(11):584-95.
3
Infectious disease in the malnourished.
Med Clin North Am. 1970 Nov;54(6):1495-508.
4
Delayed-type hypersensitivity to Staphylococcus aureus in human subjects.人类受试者对金黄色葡萄球菌的迟发型超敏反应。
J Reticuloendothel Soc. 1970 Nov;8(5):493-8.
5
Tuberculin test in children with malnutrition.营养不良儿童的结核菌素试验。
Br Med J. 1968 Aug 31;3(5617):529-31. doi: 10.1136/bmj.3.5617.529.
6
The clinical pattern of protein-calorie malnutrition in Ibadan, Nigeria.尼日利亚伊巴丹蛋白质 - 热量营养不良的临床模式。
West Afr Med J Niger Pract. 1971 Oct;20(5):313-9.
7
Nutrition and tuberculosis. Diet and susceptibility to tuberculosis.
Postgrad Med. 1971 Dec;50(6):53-6. doi: 10.1080/00325481.1971.11697695.
8
Immunoglobulin levels in protein calorie malnutrition.蛋白质热量营养不良中的免疫球蛋白水平。
S Afr Med J. 1971 Sep 4;45(35):980-2.
9
Transferrin and Staphylococcus aureus in kwashiorkor.夸希奥科病中的转铁蛋白和金黄色葡萄球菌
Am J Clin Pathol. 1972 May;57(5):587-91. doi: 10.1093/ajcp/57.5.587.
10
Generalized herpes simplex in malnourished children.营养不良儿童的全身性单纯疱疹
J Clin Pathol. 1970 Feb;23(1):24-30. doi: 10.1136/jcp.23.1.24.
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