Okoth F A, Lule G N, Ogutu E O, Pilczer S, Dubois C
Kenya Medical Research Institute, (KEMRI), Nairobi.
East Afr Med J. 1994 Jan;71(1):44-8.
Famotidine has been used for the treatment of peptic ulcers and Zollinger Ellison syndrome and is also useful in reflux and erosive oesophagitis. To evaluate the effects of Famotidine 20 mg given twice daily in the symptomatic relief of gastro-oesophageal reflux disease with normal oesophagus or mild endoscopic oesophagitis, patients were followed over a period of six weeks. 70% of the patients had complete day-time heartburn relief during the study and 75% had complete night-time heartburn relief during the study. Famotidine was found to be safe and there were no serious clinical or laboratory adverse experiences.
法莫替丁已被用于治疗消化性溃疡和卓艾综合征，对反流性食管炎和糜烂性食管炎也有效。为评估每日两次服用20毫克法莫替丁对食管正常或轻度内镜下食管炎的胃食管反流病症状缓解的效果，对患者进行了为期六周的随访。70%的患者在研究期间白天烧心症状完全缓解，75%的患者在研究期间夜间烧心症状完全缓解。结果发现法莫替丁是安全的，没有严重的临床或实验室不良事件。
