Koehler B, Kozłowska A
Children Endocrine Diseases Clinic, Silesian Medical Academy, Katowice.
Endokrynol Pol. 1993;44(3):305-9.
Geographical region of Katowice is situated in an upland built of carbonate rocks, often with predominance of loss. A randomized trial was carried out in the urban population of this area. 1080 children aged 7-13 were examined. In 505 urine iodine was measured. 17.5% of the examined children had enlarged thyroid glands (Ib, II, III) in palpation, 82.3% did not have goiter (O, Ia). Interviews with patients revealed that 48.8% of the examined children used iodized salt, while 51.2% did not. Mean urine iodine concentration was 70.6 micrograms/l. No correlation between use of iodized salt, urine iodine concentration, and goiter was found. However, prevalence of goiter and low urine concentration suggested deficiency of this microelement in the examined industrial region. Therefore there is need for further investigations and for a profound change of the existing ineffective iodine prophylaxis.
卡托维兹的地理区域位于由碳酸盐岩构成的高地，通常以流失为主。在该地区的城市人口中进行了一项随机试验。对1080名7至13岁的儿童进行了检查。对其中505名儿童测量了尿碘。在触诊中，17.5%的受检儿童甲状腺肿大（Ib、II、III度），82.3%没有甲状腺肿（O、Ia度）。对患者的访谈显示，48.8%的受检儿童使用加碘盐，而51.2%未使用。尿碘平均浓度为70.6微克/升。未发现加碘盐的使用、尿碘浓度与甲状腺肿之间存在相关性。然而，甲状腺肿的患病率和低尿碘浓度表明，在受检的工业区这种微量元素缺乏。因此，需要进一步调查，并对现有的无效碘预防措施进行深刻变革。
