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新的缩醛磷脂酰甘油的分离与表征。梭菌中的一族醚脂。

Isolation and characterization of new phosphatidylglycerol acetals of plasmalogens. A family of ether lipids in clostridia.

作者信息

Johnston N C, Goldfine H

机构信息

Department of Microbiology, University of Pennsylvania, School of Medicine, Philadelphia 19104-6076.

出版信息

Eur J Biochem. 1994 Aug 1;223(3):957-63. doi: 10.1111/j.1432-1033.1994.tb19073.x.

DOI:10.1111/j.1432-1033.1994.tb19073.x
PMID:8055972
Abstract

A new phosphatidylglycerol acetal of cardiolipin plasmalogen has been isolated from Clostridium innocuum. The structure was derived from the results of quantitative group analyses, the identification of the products of acid hydrolysis, alkaline methanolysis, hydrolysis by a cardiolipin-specific phospholipase D and by one- and two-dimensional proton NMR. Two other minor ether phospholipids: the lyso form of the phosphatidylglycerol acetal of cardiolipin plasmalogen, and the phosphatidylglycerol acetal of plasmenylglycerol have been identified in C. innocuum lipid extracts.

摘要

一种新的心磷脂缩醛磷脂酰甘油已从无害梭菌中分离出来。其结构来源于定量基团分析结果、酸性水解产物、碱性甲醇解产物、心磷脂特异性磷脂酶D水解产物以及一维和二维质子核磁共振鉴定结果。在无害梭菌脂质提取物中还鉴定出了另外两种次要的醚磷脂:心磷脂缩醛磷脂酰甘油的溶血形式以及缩醛磷脂酰甘油的磷脂酰甘油缩醛。

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