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苯并[c]菲啶生物碱血根碱和白屈菜红碱：生物活性及口腔护理应用

Benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine: biological activities and dental care applications.

作者信息

Walterová D, Ulrichová J, Válka I, Vicar J, Vavrecková C, Táborská E, Harjrader R J, Meyer D L, Cerná H, Simánek V

机构信息

Institute of Medical Chemistry, Faculty of Medicine, Palacký University Olomouc, Czech Republic.

出版信息

Acta Univ Palacki Olomuc Fac Med. 1995;139:7-16.

PMID:8686560
Abstract

This article reviews chemical, pharmacological, and toxicological research relating to two principal benzo[c]phenanthridine alkaloids, namely sanguinarine and chelerythrine, in the period 1980-1994. The medical applications of these alkaloids in relation to their biological activities are discussed.

摘要

本文回顾了1980年至1994年期间与两种主要的苯并[c]菲啶生物碱即血根碱和白屈菜红碱相关的化学、药理学和毒理学研究。讨论了这些生物碱在医学上与其生物活性相关的应用。

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Benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine: biological activities and dental care applications.苯并[c]菲啶生物碱血根碱和白屈菜红碱：生物活性及口腔护理应用
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DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique.通过32P后标记技术揭示的季铵型苯并[c]菲啶生物碱血根碱和白屈菜红碱的DNA加合物形成
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