Kolesova O K, Vetrilé L A, Popova O A, Makeenok O E
Patol Fiziol Eksp Ter. 1993 Mar-Apr(2):5-7.
The effect of antibodies to serotonin on lipid peroxidation (LPO) in acute alcoholic intoxication was studied in rabbit experiments. Acute alcoholization causes marked LPO disorders which are manifested by a sharp increase of the content of intermediate products and reduction of the concentration of end products. Active immunization of the animals with a conjugated serotonin antigen, bovine serum albumin, reduces the LPO disorders induced by alcoholization.
在兔实验中研究了血清素抗体对急性酒精中毒时脂质过氧化(LPO)的影响。急性酒精化会导致明显的LPO紊乱,表现为中间产物含量急剧增加和终产物浓度降低。用结合血清素抗原、牛血清白蛋白对动物进行主动免疫,可减轻酒精化诱导的LPO紊乱。