Barbarash N A, Khaliulin I G, Bykova O V
Patol Fiziol Eksp Ter. 1993 May-Jun(3):10-2.
Occlusion of the left coronary artery under general anesthesia and reperfusion were conducted in male Wistar rats adapted to cold, exercise during swimming and to the alternation of these effects. Adaptation facilitated reduction in the occurrence of arrhythmias and depression of contractile activity of the heart under these conditions. Although among the three types of adaptational effects, exercise induced the most marked development of the myocardial capillary network, its alternation with cold prevented more effectively the development of disorders of heart rhythm and contractility caused by ischemia and reperfusion.
对适应寒冷、游泳运动以及这两种效应交替变化的雄性Wistar大鼠实施全身麻醉下的左冠状动脉闭塞和再灌注。在这些条件下，适应有助于减少心律失常的发生以及心脏收缩活动的抑制。尽管在这三种适应效应中，运动诱导心肌毛细血管网络发育最为显著，但其与寒冷交替能更有效地预防缺血和再灌注引起的心律和收缩性紊乱的发展。
