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[Central pontine myelinolysis: apropos of an oligosymptomatic form].

作者信息

Meyer P, Jouanny P, Laurain M C, Bollaërt P E, Braun M, Mallié J P, Jeandel C

机构信息

Service de médecine B, hôpitaux de Brabois, CHU de Nancy, France.

出版信息

Rev Med Interne. 1994 Apr;15(4):282-6. doi: 10.1016/s0248-8663(94)80034-0.

Abstract

The authors report a case of paucisymptomatic central pontine myelinolysis (CMP). A 66 years old female had severe hypochloronatremia and hypokaliemia due to diuretic. Despite a slow hydroelectrolytic correction, she presented with dumbness and seizure. CT scan showed hypodensity of protuberance and magnetic resonance imaging (MRI) shown hypersignal of protuberance and undercortex, compatible with central and extra pontine myelinolysis. The long term clinical outcome was good, as MRI's data. Rapid and important correction of severe hyponatremia should be the most important factors of demyelination, secondary to interference with cerebral adaptation mechanisms to hypoosmolality. These factors were not present in this case.

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