Rubinstein D, Youngman V, Hise J H, Damiano T R
University of Colorado Health Sciences Center, Department of Radiology, Denver 80262.
AJNR Am J Neuroradiol. 1994 May;15(5):869-75.
To determine whether the MR findings of callosal dysgenesis suggest that the partially formed corpus callosum in humans is the result of arrested growth or delayed continued development.
The MR scans of 25 patients with callosal dysgenesis were reviewed to determine whether the observed corpus callosum corresponded to the form and position of a portion of a normal corpus callosum, as suggested by a theory of arrested growth.
In 10 of the 25 cases, the partially formed corpus callosum corresponded to a portion of a normal corpus callosum. In the remaining 15 cases, the partially formed corpus callosum was located posterior to the expected location of a normal genu and inferior to the expected location of a normal body.
Corpus callosum dysgenesis in humans may be caused by arrested growth in some cases; in other cases it is most likely caused by delayed continued development that attempts to compensate for earlier abnormalities in the evolution of midline structures.
确定胼胝体发育不全的磁共振成像(MR)表现是否表明人类部分形成的胼胝体是生长停滞或持续发育延迟的结果。
回顾了25例胼胝体发育不全患者的MR扫描结果,以确定观察到的胼胝体是否与生长停滞理论所提示的正常胼胝体一部分的形态和位置相符。
25例中有10例,部分形成的胼胝体与正常胼胝体的一部分相对应。在其余15例中,部分形成的胼胝体位于正常膝部预期位置的后方,且在正常体部预期位置的下方。
人类胼胝体发育不全在某些情况下可能由生长停滞引起;在其他情况下,很可能是由持续发育延迟导致的,这种延迟试图补偿中线结构演化早期出现的异常。