Bhuva M, Ganger D, Jensen D
Department of Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.
Am J Med. 1994 Aug;97(2):169-75. doi: 10.1016/0002-9343(94)90027-2.
Spontaneous bacterial peritonitis (SBP) is a serious complication in patients with cirrhotic ascites. Greater understanding of the pathogenesis and risk factors for the development of SBP recently has improved our ability to prevent and treat the infection. The decreased threshold for performing diagnostic paracentesis in cirrhotic patients coupled with the use of non-nephrotoxic antibiotics have resulted in decreasing mortality rates for patients with SBP. Despite these advances, recurrence is common and often fatal. Thus, the prevention of SBP by diuresis and oral antibiotic prophylaxis has recently been studied. This review summarizes the recent developments in SBP, with an emphasis on patient management and prevention of SBP.
自发性细菌性腹膜炎（SBP）是肝硬化腹水患者的一种严重并发症。近年来，对SBP发病机制和危险因素的深入了解提高了我们预防和治疗该感染的能力。肝硬化患者诊断性腹腔穿刺阈值的降低以及非肾毒性抗生素的使用，使得SBP患者的死亡率有所下降。尽管取得了这些进展，但复发很常见且往往致命。因此，最近对通过利尿和口服抗生素预防SBP进行了研究。本综述总结了SBP的最新进展，重点是患者管理和SBP的预防。
