Kawakami E, Fagundes-Neto U
Departamento de Pediatria, Escola Paulista de Medicina, São Paulo.
Arq Gastroenterol. 1993 Oct-Dec;30(4):99-106.
There are several different oral hydration solutions of variable composition commercially available besides WHO 90. The purpose of this paper was to establish the type of solution more favorable to hydroelectrolytic transport. Water, Na and glucose transport of oral hydration solutions were measured by analysis of 728 samples from perfusions with 7 different solutions in jejunal loops of rats "in vivo". The following solutions were studied: homemade (96), Rehidrat (96), Hydrax (104), WHO 90 (104), WHO 60 (112), Pedyalite 30 (104), Pedyalite 90 (112) and a control solution (144). Hypotonic solutions with a molar ratio Na/glucose 2:1, had the greatest water absorption (homemade and WHO 60), while the solution with 90 mEq/L of Na had the greatest absorption of this ion (Pedyalite 90, WHO 90). Regarding glucose transport, Pedyalite 90 promoted the greater absorption (25 g/L). Solution with 30 mEq/L of Na and high osmolality resulted in water and Na secretion (Pedyalite 30).
除了世卫组织90配方口服补液盐外，市面上还有几种成分各异的口服补液溶液可供选择。本文旨在确定哪种溶液类型更有利于水电解质转运。通过对大鼠空肠袢“体内”灌注7种不同溶液得到的728个样本进行分析，测定了口服补液溶液的水、钠和葡萄糖转运情况。研究了以下几种溶液：自制溶液（96例）、瑞迪拉特（96例）、海德拉克斯（104例）、世卫组织90配方口服补液盐（104例）、世卫组织60配方口服补液盐（112例）、小儿电解质液30（104例）、小儿电解质液90（112例）以及一种对照溶液（144例）。钠/葡萄糖摩尔比为2:1的低渗溶液水吸收量最大（自制溶液和世卫组织60配方口服补液盐），而钠含量为90 mEq/L的溶液该离子吸收量最大（小儿电解质液90、世卫组织90配方口服补液盐）。关于葡萄糖转运，小儿电解质液90促进吸收效果更佳（25 g/L）。钠含量为30 mEq/L且渗透压高的溶液导致水和钠分泌（小儿电解质液30）。
