Henderson R J, Hill D M, Vickers A A, Edwards J M, Tillett H E
Br Med J. 1975 Jun 21;2(5972):656-9. doi: 10.1136/bmj.2.5972.656.
Forty-six veterinary surgeons were given a full clinical examination, serological examinations with estimates of immunoglobulins, and supplementary haematological and radiological investigations. Thirty-five complained of one or more symptoms, and eight had abnormal physical signs which might have been caused by infection with Brucella abortus, but neither sereological tests results nor immunoglobulin estimates bore any special relation to the clinical features. The soundest way of assessing ill health which had possibly been caused by brucellosis seemed to be thorough clinical examination and disregard of serologican findings. Interpreting results by the usual serological tests in the absence of a clinical examination is probably of doubtful value and may even be misleading.
对46名兽医进行了全面的临床检查、免疫球蛋白测定的血清学检查以及补充的血液学和放射学检查。35人抱怨有一个或多个症状,8人有异常体征,这些体征可能是由流产布鲁氏菌感染引起的,但血清学检测结果和免疫球蛋白测定与临床特征均无特殊关联。评估可能由布鲁氏菌病引起的健康不佳的最可靠方法似乎是进行全面的临床检查,而忽略血清学检查结果。在没有临床检查的情况下,通过常规血清学检测来解释结果可能价值存疑,甚至可能产生误导。