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间日疟原虫萨尔瓦多I株子孢子传播的进一步研究

Further studies on the sporozoite transmission of the Salvador I strain of Plasmodium vivax.

作者信息

Collins W E, Morris C L, Richardson B B, Sullivan J S, Galland G G

机构信息

Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341.

出版信息

J Parasitol. 1994 Aug;80(4):512-7.

PMID:8064516
Abstract

Different species of Saimiri and Aotus monkeys were inoculated with sporozoites of the Salvador I strain of Plasmodium vivax. Of 58 Saimiri inoculated, 45 developed parasitemia (4 following bites and 41 following intravenous inoculation). Prepatent periods ranged from 10 to 63 days. Twelve of 19 monkeys inoculated with sporozoites that had been stored frozen developed patent parasitemia after 16-53 days. Of 41 Aotus monkeys inoculated, only 10 (2 via bites and 8 via intravenous inoculation) developed parasitemia. One of 7 Aotus inoculated with sporozoites that had been frozen developed parasitemia with a prepatent period of 26 days. Mosquitoes were infected by feeding on gametocytes from Aotus and Saimiri monkeys, chimpanzees, and a human. Sporozoites from Anopheles stephensi, Anopheles freeborni, Anopheles dirus, and Anopheles gambiae induced infection.

摘要

将不同种类的松鼠猴和夜猴接种间日疟原虫萨尔瓦多I株的子孢子。在接种的58只松鼠猴中,45只出现了寄生虫血症(4只通过叮咬感染,41只通过静脉接种感染)。潜伏期为10至63天。19只接种了冷冻保存子孢子的猴子中有12只在16 - 53天后出现了显性寄生虫血症。在接种的41只夜猴中,只有10只(2只通过叮咬感染,8只通过静脉接种感染)出现了寄生虫血症。7只接种了冷冻子孢子的夜猴中有1只出现了寄生虫血症,潜伏期为26天。通过吸食来自夜猴、松鼠猴、黑猩猩和人类的配子体,蚊子被感染。来自斯氏按蚊、弗里伯恩按蚊、大劣按蚊和冈比亚按蚊的子孢子可引发感染。

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J Parasitol. 1994 Aug;80(4):512-7.
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