Blumenthal H T, Mayfield R
Department of Community and Family Medicine, St Louis University School of Medicine, MO 63104.
J Natl Med Assoc. 1994 Jul;86(7):500-5.
This article presents data on total cholesterol (TC) determinations carried out in black patients of an inner-city neighborhood health center. In the pediatric group (under age 18), TC determinations were carried out only in over-weight children. In adults, they were performed routinely on all new admissions. During 1992, a total of 1158 TC determinations were made, 385 in males and 773 in females. Age-related changes in mean TC were compared between black males and females, between males in our population and those in the general population, and between females in the two populations. Age-related changes in the proportion of cases in our population also were analyzed in the desirable, borderline, and high-risk TC levels. Our objective was to determine if these data could account for the higher black mortality rates from coronary heart disease (CHD) than in the general population. The data show that mean TC levels and risk ratios are not substantially different in our population than in the general population. The differences in CHD mortality rates in the two populations, therefore, cannot be attributed to TC levels.
本文介绍了在市中心区社区健康中心对黑人患者进行总胆固醇(TC)测定的数据。在儿科组(18岁以下),仅对超重儿童进行了TC测定。在成人中,对所有新入院患者都进行了常规测定。1992年期间,共进行了1158次TC测定,其中男性385次,女性773次。比较了黑人男性和女性之间、我们研究人群中的男性与一般人群中的男性之间以及这两个人群中的女性之间平均TC的年龄相关变化。还分析了我们研究人群中处于理想、临界和高风险TC水平的病例比例的年龄相关变化。我们的目的是确定这些数据是否可以解释黑人冠心病(CHD)死亡率高于一般人群的原因。数据表明,我们研究人群中的平均TC水平和风险比与一般人群相比没有实质性差异。因此,两个人群中CHD死亡率的差异不能归因于TC水平。