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玻利维亚圣克鲁斯省科迪勒拉省先前未接种疫苗儿童接种疫苗前后的麻疹抗体患病率。

Prevalence of measles antibodies before and after vaccination in previously unvaccinated children of the Cordillera Province (Santa Cruz Department, Bolivia).

作者信息

Guglielmetti P, Bianchi Bandinelli M L, Bartoloni A, Gamboa H, Roselli M, Valensin P E

机构信息

Institute of Infectious Diseases, University of Siena, Italy.

出版信息

J Trop Med Hyg. 1994 Aug;97(4):231-5.

PMID:8064946
Abstract

A study was carried out in the Cordillera Health District (Santa Cruz Department, Bolivia) from October 1988 to April 1989 to determine the seroprevalence of measles antibodies and the seroconversion rates among a group of previously unvaccinated children (9-36 months of age) from the urban and rural area of the province, before and after immunization with a standard dose of Schwarz measles vaccine. Among 265 previously unvaccinated children, 77 (29%) had measles IgG antibodies prior to immunization; 141 out of 147 (96%) seronegative children at the time of vaccination seroconverted. No difference in seroprevalence and in seroconversion rates was found between the urban and rural groups.

摘要

1988年10月至1989年4月期间,在科迪勒拉健康区(玻利维亚圣克鲁斯省)开展了一项研究,以确定该省城乡地区一组先前未接种疫苗的儿童(9至36个月大)在接种标准剂量的施瓦茨麻疹疫苗前后的麻疹抗体血清阳性率和血清转化率。在265名先前未接种疫苗的儿童中,77名(29%)在免疫前有麻疹IgG抗体;接种疫苗时147名血清阴性儿童中有141名(96%)发生了血清转化。城乡组之间在血清阳性率和血清转化率方面未发现差异。

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