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[结核病的主动流行病学监测]

[Active epidemiologic surveillance of tuberculosis].

作者信息

Medina E

机构信息

Escuela de Salud Pública, Facultad de Medicina, Universidad de Chile.

出版信息

Rev Med Chil. 1994 Jan;122(1):102-8.

PMID:8066337
Abstract

With 5,000 new active cases each year, tuberculosis in Chile remains as the most important communicable disease in the country. Since the type of control programs are linked to the epidemiologic situation as far as infection, morbidity and mortality are concerned, an effective surveillance system is needed, with analysis of the general data and an active search for other evidences which show the advantages and problems of the control programs. The number of active cases shows a downward trend with 66 new cases per 100,000 population in 1982 and 37 in 1992. nevertheless, in Santiago, comparing years 1991 and 1991, an increase of 4% in morbidity, 37% of mortality and 33% in the case fatality rate are observed. Morbidity rates are variable with highest numbers in the I Region of Tarapacá probably linked to the prevalent ethnic type of the population. One quarter out of total tuberculosis deaths depends on the late effects of the disease and three quarter are the consequences of recent active disease. People over 55 years of age represents 25% out of total new cases. Besides classical indicators it is important to consider the frequency and results of the practice of diagnostic laboratory tests; the antibiotic therapy resistance; the results of the treatment, analyzing cohorts of treated people; the importance of different infection factors; the evaluation of BCG immunization; the meaning of animal tuberculosis infection; the slowness in the beginning of treatment in new cases; the results of the screening of high risk population and the systematic analysis of each death due to tuberculosis.

摘要

智利每年有5000例新发病例,结核病仍是该国最重要的传染病。由于控制项目的类型与感染、发病率和死亡率方面的流行病学情况相关,因此需要一个有效的监测系统,包括对一般数据的分析以及积极寻找其他能表明控制项目优缺点的证据。新发病例数呈下降趋势,1982年每10万人口中有66例新病例,1992年为37例。然而,在圣地亚哥,比较1991年和1991年,发病率增加了4%,死亡率增加了37%,病死率增加了33%。发病率各不相同,塔拉帕卡第一大区的发病率最高,这可能与该地区人口的主要种族类型有关。结核病死亡总数的四分之一归因于疾病的晚期影响,四分之三是近期活动性疾病的后果。55岁以上的人群占新病例总数的25%。除了经典指标外,还需要考虑诊断实验室检测的频率和结果;抗生素治疗耐药性;治疗结果,分析接受治疗人群的队列;不同感染因素的重要性;卡介苗免疫的评估;动物结核病感染的意义;新病例开始治疗的迟缓情况;高危人群筛查结果以及对每例结核病死亡病例的系统分析。

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