Jespersen H F, Cortsen M E, Videbaek H
Ugeskr Laeger. 1994 Jul 25;156(30):4348-51.
Thrombosis of intracranial sinuses and veins is a rare but potentially lethal syndrome. It often affects young adults, but occurs in all ages. It is frequently seen in association with hormonal changes (puerperium, pregnancy and the use of oral contraceptives), inflammatory bowel disease, cancer, and various states of hypercoagulability, or as a consequence of infection. The clinical picture is extremely variable and the diagnosis can be difficult unless one specifically searches for it. The combination of magnetic resonance imaging and magnetic resonance angiography is a powerful and non-invasive tool for diagnosing the syndrome. Treatment with heparin (and for the septic form antibiotics) improves the outcome.
颅内静脉窦和静脉血栓形成是一种罕见但可能致命的综合征。它常影响年轻人,但各年龄段均可发生。常见于与激素变化(产褥期、妊娠及口服避孕药的使用)、炎症性肠病、癌症、各种高凝状态相关的情况,或作为感染的后果出现。临床表现极为多样,除非专门进行排查,否则诊断可能困难。磁共振成像和磁共振血管造影相结合是诊断该综合征的有力且无创的工具。使用肝素(以及针对感染性类型使用抗生素)进行治疗可改善预后。