Dulit R A, Fyer M R, Leon A C, Brodsky B S, Frances A J
Department of Psychiatry, Cornell University Medical Center, New York, NY.
Am J Psychiatry. 1994 Sep;151(9):1305-11. doi: 10.1176/ajp.151.9.1305.
This exploratory study sought demographic and clinical correlates of self-mutilation (self-injury without suicidal intent) in borderline personality disorder.
Among 124 consecutively admitted inpatients with borderline personality disorder, there were 62 who did not mutilate themselves, 23 who mutilated themselves infrequently (fewer than five lifetime events), and 39 who mutilated themselves frequently (five or more lifetime events); each received ratings on numerous measures of psychopathology.
Compared to nonmutilators, frequent mutilators were significantly more likely to be in outpatient treatment at the time of admission and had more weeks of prior outpatient and inpatient treatment; they were also more likely to receive comorbid diagnoses of current major depression, anorexia nervosa, and bulimia nervosa. Frequent mutilators had significantly higher group means on the Beck Scale for Suicidal Ideation, were more likely to have attempted suicide, and were more likely to have attempted suicide more often than both infrequent mutilators and nonmutilators. The adjusted odds ratios from logistic regression analyses demonstrated that major depression, bulimia nervosa, number of prior suicide attempts, and acute suicidal ideation were each associated with greater risk of frequent mutilation.
Borderline patients who frequently mutilate themselves may represent a subgroup of especially high utilizers of psychiatric treatment who are at particularly high risk for suicidal behavior and for comorbid major depression and eating disorders. Clinicians should consider aggressive treatment of comorbid axis I disorders and careful assessment of suicide risk in these patients.
本探索性研究旨在寻找边缘性人格障碍患者中自我伤害行为(无自杀意图的自我伤害)的人口统计学和临床相关因素。
在124例连续入院的边缘性人格障碍患者中,62例无自我伤害行为,23例自我伤害行为不频繁(一生少于5次),39例自我伤害行为频繁(一生5次或更多);每例患者均接受多项精神病理学测量的评分。
与无自我伤害行为者相比,频繁自我伤害行为者在入院时更有可能接受门诊治疗,且之前接受门诊和住院治疗的周数更多;他们也更有可能被诊断为合并当前重度抑郁症、神经性厌食症和神经性贪食症。频繁自我伤害行为者在贝克自杀意念量表上的组均数显著更高,更有可能尝试过自杀,且比自我伤害行为不频繁者和无自我伤害行为者更有可能多次尝试自杀。逻辑回归分析的校正比值比表明,重度抑郁症、神经性贪食症、之前自杀未遂次数和急性自杀意念均与频繁自我伤害行为的更高风险相关。
频繁自我伤害的边缘性人格障碍患者可能代表了一类特殊的高精神科治疗利用率亚组,他们具有特别高的自杀行为风险以及合并重度抑郁症和饮食失调症的风险。临床医生应考虑积极治疗合并的轴I障碍,并仔细评估这些患者的自杀风险。