惊恐障碍患者特征的对照比较。

Controlled comparison of the characteristics of patients with panic disorder.

作者信息

Simpson R J, Kazmierczak T, Power K G, Sharp D M

机构信息

Bridge of Allan, Stirlingshire.

出版信息

Br J Gen Pract. 1994 Aug;44(385):352-6.

PMID:8068393

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1238951/

Abstract

BACKGROUND

Increased general practice attendance rates have been associated with the diagnosis of mental illness but panic disorder has not been specifically investigated in this respect. In addition, studies have failed adequately to assess type and frequency of secondary care referral and patterns of psychotropic prescription in patients with panic disorder in relation to matched controls.

AIM

This study set out to compare subjects with panic disorder with age and sex matched controls on measures of general practice consultation rate; psychotropic and non-psychotropic drug use; referral to secondary care, laboratory and radiological tests and hospital admissions; history of illness and complaints; and psychiatric comorbidity.

METHOD

The study was carried out in nine practices in the Forth Valley area. One hundred patients with panic disorder, previously diagnosed using DSM III-R criteria, were identified and matched by age and sex with controls. Data were collected by review of general practice case notes.

RESULTS

Subjects with panic disorder had significantly higher rates of general practice consultation over the 10 year period prior to DSM III-R diagnosis of panic disorder than controls. Subjects with panic disorder had also been prescribed a significantly greater number of psychotropic and non-psychotropic medications over this period, had had more secondary care investigations and had higher rates of mainly minor illness and related complaints than controls. High comorbidity of panic disorder with depression which had been diagnosed over the 10 year period prior to DSM III-R diagnosis of panic disorder was found.

CONCLUSION

The results of this study describe a population of subjects with panic disorder who are long-term heavy users of primary care services. The results also suggest an association between panic disorder and both minor illness and psychiatric comorbidity over the 10 year period prior to DSM III-R diagnosis of panic disorder.

摘要

背景

全科医疗就诊率的增加与精神疾病的诊断相关，但惊恐障碍在这方面尚未得到专门研究。此外，研究未能充分评估惊恐障碍患者与匹配对照组相比的二级医疗转诊类型和频率以及精神药物处方模式。

目的

本研究旨在比较惊恐障碍患者与年龄和性别匹配的对照组在全科医疗咨询率、精神药物和非精神药物使用、转诊至二级医疗、实验室和放射学检查以及住院情况、疾病史和主诉、以及精神共病方面的差异。

方法

该研究在福斯谷地区的九个医疗机构开展。确定了100名先前根据DSM III-R标准诊断为惊恐障碍的患者，并按年龄和性别与对照组进行匹配。通过查阅全科医疗病历收集数据。

结果

在根据DSM III-R诊断惊恐障碍之前的10年期间，惊恐障碍患者的全科医疗咨询率显著高于对照组。在此期间，惊恐障碍患者还被开具了显著更多的精神药物和非精神药物，接受了更多的二级医疗检查，主要患有轻微疾病及相关主诉的比例也高于对照组。发现在根据DSM III-R诊断惊恐障碍之前的10年期间，惊恐障碍与抑郁症的共病率较高。