Grech E D, Ramsdale D R
Department of Cardiology, Cardiothoracic Centre, Liverpool.
Br Heart J. 1994 Jul;72(1):94-5. doi: 10.1136/hrt.72.1.94.
Reperfusion arrhythmias may be a cause of sudden death in acute myocardial infarction. A patient underwent successful coronary artery recanalisation by primary percutaneous transluminal coronary angioplasty (PTCA) for acute myocardial infarction. In this patient an idioventricular rhythm with a severe haemodynamic effect developed within one minute of deflation of the PTCA balloon. Sinus rhythm was immediately restored by reinflating the balloon and thus reinterrupting the supply of oxygenated blood. This suggests that reperfusion with consequent reoxygenation is a primary factor in arrhythmogenesis.
再灌注心律失常可能是急性心肌梗死患者猝死的原因之一。一名患者因急性心肌梗死接受了直接经皮冠状动脉腔内血管成形术(PTCA),成功实现了冠状动脉再通。在该患者中,PTCA球囊放气后一分钟内出现了具有严重血流动力学影响的室性自主心律。通过重新充盈球囊,从而再次中断含氧血液供应,窦性心律立即恢复。这表明再灌注及随之而来的再氧合是心律失常发生的主要因素。