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[切尔诺贝利核电站事故区域内受辐射大鼠肝脏DNA的水合作用及结构状态]

[Hydration and structural state of liver DNA of rats exposed to radiation in the Chernobyl AES zone].

作者信息

Semenov M A, Bol'bukh T V, Krasnitskaia A A, Maleev V Ia

出版信息

Radiats Biol Radioecol. 1994 May-Jun;34(3):328-35.

PMID:8069363
Abstract

By methods of IR-spectroscopy, electrophoresis and piezomicrobalance the comparative study on hydration and structural state of liver DNA from rats both intact and exposed within the Chernobyl accident zone was conducted. Modification of primary and secondary DNA structure in irradiated animals demonstrate serious disturbance of hepatocyte genetic apparatus. This is responsible for previously found considerable morphologic and ultra-structural changes in rat liver tissue after prolonged exposure to low-level ionizing radiation in the Chernobyl accident zone.

摘要

通过红外光谱、电泳和压电微天平等方法,对来自切尔诺贝利事故区未受辐射和受辐射大鼠的肝脏DNA的水合作用和结构状态进行了比较研究。受辐射动物体内DNA一级和二级结构的改变表明肝细胞遗传装置受到严重干扰。这与之前在切尔诺贝利事故区长期暴露于低水平电离辐射后大鼠肝脏组织中发现的显著形态学和超微结构变化有关。

相似文献

1
[Hydration and structural state of liver DNA of rats exposed to radiation in the Chernobyl AES zone].[切尔诺贝利核电站事故区域内受辐射大鼠肝脏DNA的水合作用及结构状态]
Radiats Biol Radioecol. 1994 May-Jun;34(3):328-35.
2
[The biological effects in animals related to the accident at the Chernobyl Atomic Electric Power Station. 4. The morphological and ultrastructural changes in the liver of rats].[与切尔诺贝利原子能发电站事故相关的动物生物学效应。4. 大鼠肝脏的形态学和超微结构变化]
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[An attempt at a polythetic classification of a group of clean up team workers after the Chernobyl AES accident].[对切尔诺贝利核电站事故后清理团队工作人员进行多特征分类的尝试]
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Nuclear accident crisis and liver disease: a summary on evidences.核事故危机与肝脏疾病:证据综述
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