Shevchenko A S, Konopleva I V, Tkachuk E Kh
Radiats Biol Radioecol. 1994 May-Jun;34(3):379-85.
It was found that the total Ca content in erythrocytes from irradiated sheep and horses increased by 10-40% from 1st till 5th days after irradiation, the intracellular Mg content being unchanged. More than 2-fold increase in total Ca content in lymphocytes during first 15 days was revealed, while in platelets only a trend for a growth in acute period of radiation disease was detected. On the contrary, no reliable changes in total Ca content in plasma after irradiation were observed. This fact indicates that Ca accumulation in blood cells after whole-body irradiation is due to disturbance in intracellular Ca(2+)-homeostasis.
结果发现，受辐照绵羊和马的红细胞中总钙含量在辐照后第1天至第5天增加了10% - 40%，而细胞内镁含量未变。在最初的15天里，淋巴细胞中的总钙含量增加了两倍多，而在血小板中，仅在放射病急性期检测到有增长趋势。相反，辐照后血浆中总钙含量未观察到可靠变化。这一事实表明，全身辐照后血细胞中钙的积累是由于细胞内钙稳态紊乱所致。
