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慢性淋巴细胞白血病中缺乏T和B细胞标志物的淋巴细胞

Lymphocytes devoid of T and B cell markers in chronic lymphatic leukemia.

作者信息

Nath I, Curtis J, Mangalik A, Talwar G P

出版信息

Acta Haematol. 1975;53(1):37-43. doi: 10.1159/000208153.

Abstract

Peripheral lymphocytes of 16 patients with chronic lymphatic leukemia were studied for B and T cell markers with peroxidase-labelled anti-immunogloulin antisera and complement and spontaneous rosetting techniques. Increased numbers of B cells and normal numbers of T cells were noted. A significant observation was the presence of a large proportion of circulating lymphocytes without the conventional markers for T and B cells. This finding is correlated with clinical features.

摘要

采用过氧化物酶标记的抗免疫球蛋白抗血清、补体及自发玫瑰花结技术,对16例慢性淋巴细胞白血病患者的外周淋巴细胞进行了B和T细胞标志物研究。发现B细胞数量增加,T细胞数量正常。一个重要的观察结果是,有很大比例的循环淋巴细胞缺乏传统的T和B细胞标志物。这一发现与临床特征相关。

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