Zhang S, Du L, Li G, Liu W, Wang X, Liao Q
Hua Xi Yi Ke Da Xue Xue Bao. 1994 Mar;25(1):94-7.
A clinicopathological study of 304 cases of malignant lymphomas (ML) in children in Sichuan province is reported. One hundred and sixty of them were Hodgkin's disease (HD). The ratio between males and females was 5.7 to 1. The disease was more prevalent in children aged from 5 to 9. Cervical lymph nodes were more easily involved. Extra-nodal HD wasn't found in these cases. When subtypes of HD were concerned 62.5% of cases belonged to mixed-cellularity HD. The prognosis of HD was better than that of non-Hodgkin's lymphoma (NHL). The remaining 144 cases were NHL. The ratio between males and females was 3.4 to 1. The disease was more prevalent in children aged from 4 to 14. Eighty four percent of NHL primarily originated from superficial lymph nodes and the other 16.0% of NHL was of extranodal involvement. Seventy two point nine percent of cases in this group was of high grade malignancy. Among them the lymphoblastic type of NHL occupied 44.5%. On the other hand, the follicular type of NHL was rare (0.7%). The specialities of malignant lymphomas in childhood in China are also discussed in the present report.
报告了四川省304例儿童恶性淋巴瘤（ML）的临床病理研究。其中160例为霍奇金病（HD）。男女比例为5.7比1。该疾病在5至9岁儿童中更为常见。颈部淋巴结更容易受累。这些病例中未发现结外HD。在HD亚型方面，62.5%的病例属于混合细胞型HD。HD的预后优于非霍奇金淋巴瘤（NHL）。其余144例为NHL。男女比例为3.4比1。该疾病在4至14岁儿童中更为常见。84%的NHL主要起源于浅表淋巴结，另外16.0%的NHL为结外受累。该组中72.9%的病例为高度恶性。其中，淋巴母细胞型NHL占44.5%。另一方面，滤泡型NHL很少见（0.7%）。本报告还讨论了中国儿童恶性淋巴瘤的特点。
