Cirocchi R, Cagini L, Covarelli P, Mazieri M, Severini D, Rossi P, Pacifici A, Mosci F
Istituto di Clinica Chirurgica Generale, Università degli Studi di Perugia.
Minerva Chir. 1994 Apr;49(4):247-52.
Colorectal cancer is the second most common malignancy of the adult population in the United States. It is exceeded only by lung cancer among males and breast cancer among females. Malignancies of the colon and rectum are responsible for approximately 12 per cent of all adult cancer deaths. These tumors appear as surgical urgency by intestinal obstruction for 15-20 per cent and by perforation for 3-8 per cent of all cases. It often occurs in elderly patients; in fact, urgent surgical operations are especially performed in patients older than seventy. The mortality rate for urgent surgical operation in elderly patients is about 32-54 per cent. This high mortality is even due to concurrent pathologies and particular locoregional and/or general alterations induced by tumor. The authors studied all patients older than 75 years affected by colorectal cancer and treated by choice or by urgency at Dept. of Surgery of the University of Perugia from January 1987 to February 1993 to individualize some clinical, anatomo-pathological and therapeutical significant characteristics about colorectal cancer in geriatric age.
结直肠癌是美国成年人群中第二常见的恶性肿瘤。在男性中仅次于肺癌,在女性中仅次于乳腺癌。结肠和直肠癌导致的恶性肿瘤约占所有成人癌症死亡人数的12%。在所有病例中,这些肿瘤因肠梗阻而表现为外科急症的占15% - 20%,因穿孔而表现为外科急症的占3% - 8%。它常发生于老年患者;事实上,急诊手术尤其多见于70岁以上的患者。老年患者急诊手术的死亡率约为32% - 54%。这种高死亡率甚至归因于并存的病理状况以及肿瘤引起的特定局部区域和/或全身改变。作者研究了1987年1月至1993年2月期间在佩鲁贾大学外科接受择期或急诊治疗的所有75岁以上的结直肠癌患者,以明确老年结直肠癌的一些临床、解剖病理和治疗方面的重要特征。