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牙买加与分娩期窒息相关的死亡情况。

Deaths associated with intrapartum asphyxia in Jamaica.

作者信息

Escoffery C, Greenwood R, Ashley D, Coard K, Keeling J, Golding J

机构信息

University of the West Indies.

出版信息

Paediatr Perinat Epidemiol. 1994 Apr;8 Suppl 1:119-42. doi: 10.1111/j.1365-3016.1994.tb00496.x.

Abstract

The Jamaican Perinatal Mortality Survey compared all 2069 perinatal deaths occurring during the 12 months between 1 September 1986 and 31 August 1987 with 10,086 survivors born in the 2 months of September and October 1986. The Wigglesworth classification identified 44% of the deaths as attributable to intrapartum asphyxia (IPA), and this grouping was largely confirmed by post-mortem examination where it had been carried out. About half of these babies weighted 2500 g+ and death should have been largely preventable. Comparison of the 813 IPA singleton deaths with 9919 singleton survivors using logistic regression showed independent associations with maternal employment status, the number of children in the household, maternal height, whether or not the mother was trying to get pregnant, or had ever used an intrauterine contraceptive device. Medical conditions such as syphilis, untreated vaginal infection, bleeding < 28 weeks, bleeding 28+ weeks, highest diastolic and first diastolic blood pressures and eclamptic fits antenatally were all strongly associated. Mothers who commenced antenatal care in the first trimester were at reduced risk as were those who took iron during pregnancy. There were substantial reductions in mortality in areas where better medical facilities were available. To this model, features of previous obstetric history were offered, but the only variables which entered were those relating to prior perinatal deaths and immediately preceding miscarriage and termination. Examination of specific features in the management of labour and delivery is a logical basis for the introduction of changes in practice. Caesarean section is unlikely to be appropriate but it is suggested that more active interventions in terms of use of forceps and/or vacuum extraction may be useful.

摘要

牙买加围产期死亡率调查将1986年9月1日至1987年8月31日这12个月期间发生的所有2069例围产期死亡病例与1986年9月和10月这两个月出生的10086例存活婴儿进行了比较。威格尔斯沃思分类法将44%的死亡归因于产时窒息(IPA),这一分类在进行了尸检的情况下在很大程度上得到了证实。这些婴儿中约有一半体重在2500克及以上,死亡在很大程度上应该是可以预防的。使用逻辑回归比较813例IPA单胎死亡病例与9919例单胎存活者,结果显示与母亲就业状况、家庭子女数量、母亲身高、母亲是否试图怀孕或是否曾使用宫内节育器存在独立关联。梅毒、未经治疗的阴道感染、孕28周前出血、孕28周及以后出血、最高舒张压和首次舒张压以及产前子痫发作等医疗状况都密切相关。在孕早期开始产前护理的母亲以及在孕期服用铁剂的母亲风险较低。在医疗设施较好的地区,死亡率大幅降低。在这个模型中,提供了既往产科病史的特征,但唯一进入模型的变量是与既往围产期死亡以及紧接的流产和终止妊娠相关的变量。检查分娩管理中的具体特征是引入实践变革的合理依据。剖宫产不太可能合适,但建议在使用产钳和/或真空吸引方面采取更积极的干预措施可能会有帮助。

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