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Paternity testing in the DNA era.

作者信息

Pena S D, Chakraborty R

机构信息

Núcleo de Genética Médica de Minas Gerais (GENE/MG), Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

出版信息

Trends Genet. 1994 Jun;10(6):204-9. doi: 10.1016/0168-9525(94)90257-7.

DOI:10.1016/0168-9525(94)90257-7
PMID:8073534
Abstract

Paternity can be efficiently and effectively tested using multi-allelic variable number of tandem repeat (VNTR) polymorphisms. This can be achieved by using multilocus DNA fingerprinting probes or batteries of single-locus minisatellite probes, or by PCR testing of sets of minisatellite and microsatellite loci. Although some problems of statistics and population genetics remain to be overcome, the informativeness of these hypervariable loci is so high that paternity disputes can be resolved with certainty in virtually every case.

摘要

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