Nickel J C, Sorenson R
Department of Urology, Queen's University, Kingston, Canada.
Urology. 1994 Sep;44(3):458-60. doi: 10.1016/s0090-4295(94)80117-7.
To report our early experience using transurethral microwave thermotherapy (TUMT) to treat patients with nonbacterial prostatitis (NBP) and prostatodynia.
Nineteen patients with NBP (symptoms, negative cultures, no response to antibiotics, leukocytosis in expressed prostatitic fluid) and 5 patients with prostatodynia (symptoms, negative cultures, no response to antibiotics, no leukocytosis in expressed prostatitic fluid) were treated with TUMT at interstitial temperatures of 45 degrees to 60 degrees C for 1 hour. Response was assessed by a consistent symptom severity index and global assessment of symptoms.
A marked and significant early (3 months) favorable response was noted in nearly one half of the NBP group but little benefit was found in the prostatodynia group. The treatment was associated with few adverse experiences.
TUMT appears to be a potentially effective therapy for NBP, but its real efficacy as well as the durability of the response needs to be confirmed with a randomized double-blind sham-controlled trial.
报告我们使用经尿道微波热疗（TUMT）治疗非细菌性前列腺炎（NBP）和前列腺痛患者的早期经验。
19例NBP患者（有症状，培养阴性，对抗生素无反应，前列腺液中有白细胞增多）和5例前列腺痛患者（有症状，培养阴性，对抗生素无反应，前列腺液中无白细胞增多）接受TUMT治疗，间质温度为45摄氏度至60摄氏度，持续1小时。通过一致的症状严重程度指数和症状总体评估来评估反应。
在近一半的NBP组中观察到明显且显著的早期（3个月）良好反应，但在前列腺痛组中获益甚微。该治疗相关的不良事件较少。
TUMT似乎是治疗NBP的一种潜在有效疗法，但其真正疗效以及反应的持久性需要通过随机双盲假对照试验来证实。
