Nickel J C, Sorensen R
Queens University, Kingston General Hospital, Ontario, Canada.
J Urol. 1996 Jun;155(6):1950-4; discussion 1954-5. doi: 10.1016/s0022-5347(01)66056-7.
We investigated the effectiveness and durability of transurethral microwave thermotherapy in the treatment of chronic nonbacterial prostatitis using 2 new prostatitis specific assessments in a randomized, double-blind, sham controlled trial.
Patients with nonbacterial prostatitis were randomly assigned to receive either transurethral microwave thermotherapy or sham therapy. Patients were assessed using a symptom severity index and symptom frequency questionnaire. These 2 new prostatitis symptom assessment tools were validated by applying them to 30 similar patients without prostatitis. All nonresponders received transurethral microwave thermotherapy at 3 months and were reassessed at 6 months. Long-term followup of the responder group averaged 21 months.
The symptom severity index and symptom frequency questionnaire were confirmed to be valid for symptom assessment in prostatitis patients. The transurethral microwave thermotherapy group benefited from therapy compared to the sham group. Of the sham group 50% had a favorable response after subsequent transurethral microwave thermotherapy. The 7 responders in the treatment group continued to improve during the subsequent 21 months.
Transurethral microwave thermotherapy appears to be an effective, safe and durable treatment for some patients with nonbacterial prostatitis unresponsive to traditional therapy.
在一项随机、双盲、假对照试验中，我们使用两种新的前列腺炎特异性评估方法，研究经尿道微波热疗治疗慢性非细菌性前列腺炎的有效性和持久性。
非细菌性前列腺炎患者被随机分配接受经尿道微波热疗或假治疗。使用症状严重程度指数和症状频率问卷对患者进行评估。通过将这两种新的前列腺炎症状评估工具应用于30名无前列腺炎的类似患者，对其进行了验证。所有无反应者在3个月时接受经尿道微波热疗，并在6个月时重新评估。反应者组的长期随访平均为21个月。
症状严重程度指数和症状频率问卷被证实对前列腺炎患者的症状评估有效。与假治疗组相比，经尿道微波热疗组从治疗中获益。假治疗组中有50%的患者在随后接受经尿道微波热疗后有良好反应。治疗组的7名反应者在随后的21个月中持续改善。
经尿道微波热疗似乎是一种对某些对传统治疗无反应的非细菌性前列腺炎患者有效、安全且持久的治疗方法。
