Montorsi F, Guazzoni G, Bergamaschi F, Galli L, Consonni P, Matozzo V, Barbieri L, Rigatti P
Institute of Human Anatomy, University of Milan School of Medicine, Italy.
Prostate. 1993;22(2):139-46. doi: 10.1002/pros.2990220206.
Transrectal microwave hyperthermia of the prostate was administered to 54 patients with chronic abacterial prostatitis or prostatodynia, who failed to respond to several courses of conventional therapies. Hyperthermia was delivered in 60-min long sessions with three randomly chosen regimens (1 session/week for 4 weeks; 1 session/week for 6 weeks; 2 sessions/week for 3 weeks). A prostatic temperature of 42.5 +/- 0.5 degrees C was maintained throughout the entire duration of each session. Patients were assessed pre- and postoperatively by scoring of subjective symptoms, uroflowmetry with flow nomograms, determination of residual urine volume, and transrectal ultrasonography of the prostate. At the long-term follow-up, the subjective symptom score was significantly improved in all patients. Fifty percent of the patients also reported an improvement of life quality, 47% reported their condition unchanged, and 3% reported deterioration, despite therapy. Urodynamic parameters improved but did not reach statistical significance. No major complications were encountered. Our preliminary data indicate that transrectal microwave hyperthermia of the prostate is a safe therapy that can be beneficial as a second line treatment in selected patients with recurring symptoms of abacterial prostatitis or prostatodynia, which do not respond to medical therapy.
对54例慢性非细菌性前列腺炎或前列腺痛患者进行了经直肠微波热疗，这些患者对多个疗程的传统治疗均无反应。热疗以60分钟的疗程进行，采用三种随机选择的方案（每周1次，共4周；每周1次，共6周；每周2次，共3周）。在每个疗程的整个过程中，前列腺温度维持在42.5±0.5摄氏度。术前和术后通过主观症状评分、用流量图进行尿流率测定、残余尿量测定以及前列腺经直肠超声检查对患者进行评估。在长期随访中，所有患者的主观症状评分均有显著改善。50%的患者还报告生活质量有所提高，47%的患者报告病情未变，3%的患者报告尽管接受了治疗但病情恶化。尿动力学参数有所改善，但未达到统计学意义。未出现重大并发症。我们的初步数据表明，经直肠微波热疗是一种安全的治疗方法，对于某些复发性非细菌性前列腺炎或前列腺痛症状且药物治疗无效的患者，作为二线治疗可能有益。
