Losken H W, Tschakaloff A, von Oepen R, Mooney M P, Moritz O, Michaeli W, Lalikos J, Losken A
Division of Plastic and Reconstructive Surgery, University of Pittsburgh, PA.
Ann Plast Surg. 1994 Jun;32(6):606-11. doi: 10.1097/00000637-199406000-00008.
Biodegradable plates and screws have many advantages over metal plates and screws. Plates were injection-molded and made of DL-polylactic acid. Four-hole plates were bent with the use of a heated tip to angles of 30, 45, and 60 degrees. They were inserted in the subcutaneous space in the back of rabbits. After 2 weeks, the plates straightened, suggesting that the plates had a memory. The results were confirmed by similar in vitro investigations. The in vitro experiment was repeated with tempering of the plates. The plates were heated to a temperature of 200 degrees C for 45 seconds, cooled, and then again heated to 200 degrees C for 40 seconds. This process resulted in loss of memory of the plates. After 4 weeks, there was a change of the bending angle of less than 2.5 degrees.
可生物降解的接骨板和螺钉相对于金属接骨板和螺钉具有许多优势。接骨板采用注射成型,由DL-聚乳酸制成。四孔接骨板使用加热尖端弯曲至30度、45度和60度角。将它们插入兔子背部的皮下空间。2周后,接骨板变直,表明接骨板具有记忆性。类似的体外研究证实了该结果。对接骨板进行回火处理后重复体外实验。将接骨板加热至200摄氏度并保持45秒,冷却,然后再次加热至200摄氏度并保持40秒。这个过程导致接骨板失去记忆性。4周后,弯曲角度的变化小于2.5度。